RESUMEN
Coronavirus disease 2019 caused by SARS-CoV-2 originated from China and spread across every corner of the world. The scientific interest on COVID-19 increased after WHO declared it a pandemic in the early February of 2020. In fact, this pandemic has had a worldwide impact on economy, health, and lifestyle like no other in the last 100 years. SARS-CoV-2 belongs to Coronaviridae family and causes the deadliest clinical manifestations when compared to other viruses in the family. COVID-19 is an emerging zoonotic disease that has resulted in over 383,000 deaths around the world. Scientists are scrambling for ideas to develop treatment and prevention strategies to thwart the disease condition. In this review, we have attempted to summarize the latest information on the virus, disease, prevention, and treatment strategies. The future looks promising.
Asunto(s)
Betacoronavirus/fisiología , Infecciones por Coronavirus/virología , Neumonía Viral/virología , Animales , Betacoronavirus/genética , COVID-19 , Infecciones por Coronavirus/tratamiento farmacológico , Infecciones por Coronavirus/epidemiología , Infecciones por Coronavirus/transmisión , Humanos , Pandemias , Neumonía Viral/tratamiento farmacológico , Neumonía Viral/epidemiología , Neumonía Viral/transmisión , SARS-CoV-2 , Zoonosis/tratamiento farmacológico , Zoonosis/epidemiología , Zoonosis/transmisión , Zoonosis/virologíaRESUMEN
Coronavirus disease 2019 caused by SARS-CoV-2 originated from China and spread across every corner of the world. The scientific interest on COVID-19 increased after WHO declared it a pandemic in the early February of 2020. In fact, this pandemic has had a worldwide impact on economy, health, and lifestyle like no other in the last 100 years. SARS-CoV-2 belongs to Coronaviridae family and causes the deadliest clinical manifestations when compared to other viruses in the family. COVID-19 is an emerging zoonotic disease that has resulted in over 383,000 deaths around the world. Scientists are scrambling for ideas to develop treatment and prevention strategies to thwart the disease condition. In this review, we have attempted to summarize the latest information on the virus, disease, prevention, and treatment strategies. The future looks promising.
Asunto(s)
Betacoronavirus/patogenicidad , COVID-19/epidemiología , Control de Enfermedades Transmisibles/organización & administración , Infecciones por Coronavirus/epidemiología , Pandemias , Neumonía Viral/epidemiología , Antivirales/uso terapéutico , Ataxia/diagnóstico , Ataxia/fisiopatología , Ataxia/virología , COVID-19/prevención & control , COVID-19/terapia , COVID-19/transmisión , Control de Enfermedades Transmisibles/métodos , Infecciones por Coronavirus/prevención & control , Infecciones por Coronavirus/terapia , Infecciones por Coronavirus/transmisión , Humanos , Hidroxicloroquina/uso terapéutico , Náusea/diagnóstico , Náusea/fisiopatología , Náusea/virología , Pandemias/prevención & control , Equipo de Protección Personal/provisión & distribución , Distanciamiento Físico , Neumonía Viral/prevención & control , Neumonía Viral/terapia , Neumonía Viral/transmisión , Cuarentena/métodos , Cuarentena/organización & administración , Factores de Riesgo , SARS-CoV-2 , Índice de Severidad de la Enfermedad , Vómitos/diagnóstico , Vómitos/fisiopatología , Vómitos/virologíaAsunto(s)
Betacoronavirus/patogenicidad , Infecciones por Coronavirus/epidemiología , Síndrome de Liberación de Citoquinas/epidemiología , Coagulación Intravascular Diseminada/epidemiología , Pandemias , Neumonía Viral/epidemiología , Embolia Pulmonar/epidemiología , Insuficiencia Respiratoria/epidemiología , Anticoagulantes/uso terapéutico , Antivirales/uso terapéutico , COVID-19 , Comorbilidad , Infecciones por Coronavirus/diagnóstico , Infecciones por Coronavirus/tratamiento farmacológico , Infecciones por Coronavirus/transmisión , Síndrome de Liberación de Citoquinas/diagnóstico , Síndrome de Liberación de Citoquinas/tratamiento farmacológico , Síndrome de Liberación de Citoquinas/mortalidad , Coagulación Intravascular Diseminada/diagnóstico , Coagulación Intravascular Diseminada/tratamiento farmacológico , Coagulación Intravascular Diseminada/mortalidad , Humanos , Pulmón/irrigación sanguínea , Pulmón/efectos de los fármacos , Pulmón/patología , Pulmón/virología , Neumonía Viral/diagnóstico , Neumonía Viral/tratamiento farmacológico , Neumonía Viral/transmisión , Embolia Pulmonar/diagnóstico , Embolia Pulmonar/tratamiento farmacológico , Embolia Pulmonar/mortalidad , Insuficiencia Respiratoria/diagnóstico , Insuficiencia Respiratoria/tratamiento farmacológico , Insuficiencia Respiratoria/mortalidad , SARS-CoV-2 , Análisis de Supervivencia , Oligoelementos/uso terapéutico , Vitaminas/uso terapéuticoRESUMEN
The COVID-19 pandemic has put a serious strain on health treatments as well at the economies of many nations. Unfortunately, there is not currently available vaccine for SARS-Cov-2/COVID-19. Various types of patients have delayed treatment or even routine check-ups and we are adapting to a virtual world. In many cases, surgeries are delayed unless they are essential. This is also true with regards to cancer treatments and screening. Interestingly, some existing drugs and nutraceuticals have been screened for their effects on COVID-19. Certain FDA approved drugs, vitamin, natural products and trace minerals may be repurposed to treat or improve the prevention of COVID-19 infections and disease progression. This review article will summarize how the treatments of various cancer patients has changed during the COVID-19 era as well as discuss the promise of some existing drugs and other agents to be repurposed to treat this disease.